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Effective communication and presentation skills are required. The selected applicant will keep accurate and complete records of all scientific experiments according to established procedures and ensure that these records and raw data are properly retained. The selected candidate will draft technical reports, manuscripts and patent applications, and present work to internal and external collaborators as needed.
The selected candidate also should be eligible to work in the U. Applicants to this research scientist position should possess a Ph. The selected candidate should have expertise in virology to help establish a portfolio of complex physiologically relevant 3-D tissue models as predictive screening platforms to study viral infections and drug testing.
Applicants should have additional expertise in histology, fluorescence microscopy, flow cytometry, single-cell RNA sequencing scRNAseq , and production of induced pluripotent stem cell-derived cells.
Candidates with previous experience working in a BSL3 lab and in areas such as organoids, tissue chip, cell imaging, histology and engineering of cells with biosensors will be considered favorably. Please submit, in PDF format, a cover letter that includes a research summary and describes your interest in the position, a current curriculum vitae with a complete bibliography, and the names of and contact information for 3 references, including your current supervisor, to NCATSbioprinting mail.
Selected applicants will be required to submit letters of reference to complete the hiring process. The SCTL focuses on translating human pluripotent stem cells, such as induced pluripotent stem cells, into clinical applications and drug discovery by developing innovative technologies, methods and comprehensive multi-omics data sets through differentiation into relevant cell types in 2-D and 3-D cell culture systems.
The successful candidate will have a chance to develop their skills in a highly dynamic environment, embedded in a team of passionate scientists working on a wide range of projects related to translational stem cell biology. They will have a chance to interact with experienced bioinformaticians at NCATS and collaborators at top academic institutions. The ideal candidate should have strong science communication skills; clear and effective data visualization skills; the ability to work well independently and in a team environment; creative problem-solving skills; and a proven ability to apply the cutting-edge, rigorous standards of the bioinformatics fields.
Applicants should possess a solid knowledge of R statistical programming language; familiarity with the handling, management and storage of large-scale sequencing data; and experience querying public databases, including the SRA, GEO and dbGaP.
Preferred qualifications include experience with next-generation sequencing methods on Illumina and 10x Genomics platforms e. The ideal candidate will have experience with pre-processing tools for alignment, counting or sequence analysis e. Please submit a cover letter describing your interest in the position, a current curriculum vitae with a complete bibliography, and the names of and contact information for three references to NCATSstemcellhiring mail.
DPI focuses on early stages of the translational process, from target validation to first-in-human studies. More than scientists from a variety of disciplines and across the spectrum from early-career scientists to senior leaders are responsible for advancing the diverse research portfolio of DPI. In addition to conducting cutting-edge laboratory research, DPI scientists collaborate with more than research organizations worldwide. DPI scientists work in a collaborative, team-based environment.
The postdoctoral candidate will be recruited to work on the specific projects described below and will have ample opportunities to collaborate with scientists both within and outside of NCATS on additional projects. Candidates are expected to present results of ongoing work at meetings such as internal group meetings and national conferences and submit their work for publication in scientific journals.
Postdoctoral fellows also gain additional professional skills and exposure to a variety of career paths through participation in the DPI training program. Food and Drug Administration and the U. Environmental Protection Agency to form the Tox21 program. Since , this program has utilized a quantitative high-throughput screening approach to assess a 10,compound 10K library using a group of biologically and toxicologically relevant in vitro assays. The data generated from the screening will be used to prioritize chemicals for further in-depth toxicological evaluation, identify mechanisms of chemical toxicity and develop predictive models for in vivo biological response in humans.
The selected postdoctoral fellow should be self-motivated and prepared to work on Tox21 research projects to develop physiologically relevant assays for assessment of environmental chemicals. NCATS provides a unique and exciting environment that employs state-of-art technologies enabling assay development, chemical screening and profiling for toxicology research. The fellow will perform follow-up studies e. The fellow also will interact regularly with informatics scientists to aid data analysis and interpretation.
A strong preference will be given to applicants with prior experience in in assay development, including biotransformation-capable assays, imaging technology or compound screening. He or she should possess data analysis skills and familiarity with Excel spreadsheets. The selected candidate should be an independent thinker and a team player who is able to work in an interactive, fast-paced environment.
Applicants must be eligible to work in the United States for any employer. Annual stipends are provided commensurate with experience based on the NIH Postdoctoral Intramural Research Training Award scale ; medical insurance coverage will be provided.
The position is renewable for up to five years. Please email a cover letter describing your research and career goals, a current curriculum vitae with a complete bibliography, and the names of and contact information for three references to Menghang Xia, Ph.
Applicants also should indicate when they are available to start. The review of applications review will begin immediately and will continue until the position is filled. The branch partners with external collaborators who specialize in specific disorders, creating a multidisciplinary team of innovative scientists with expertise in assay development, high-throughput and high-content screening, automation engineering, bioinformatics and various -omics technologies.
The selected postdoctoral fellow will work under the mentorship of a biology team leader in an interactive laboratory environment within the ETB. He or she will use cutting-edge cell biology and bioassay technologies to develop disease-relevant screening assays and will be involved in all aspects of implementing small molecule screening programs, including assay design, assay development and optimization, high-throughput screening, data analysis, and mechanism-of-action studies to develop assay technologies and novel pharmacological probes.
The postdoctoral candidate will need to have training in drug screening. This project includes the study of a new platinum agent for clinical development, along with an ambitious goal of screening and discovering new uses for platinum chemotherapeutic agents. The trainee will bring experience in cell biology or bioinorganic chemistry and learn to work in a team-based world-class drug discovery environment.
He or she will keep accurate and complete records of all scientific experiments according to established procedures and ensure that these records and raw data are properly retained. He or she also will draft technical reports and manuscripts and will present their work internally and to external collaborators as needed. Applicants should have or expect to receive a Ph. Applicants interested in furthering their knowledge and exposure to translational science are encouraged to apply; prior high-throughput screening experience is not a prerequisite.
Please email a cover letter describing your research and career goals, a current curriculum vitae with a complete bibliography, and the names of and contact information for three references to NCATS ETB Careers at ncatsetbcareers mail. Please note that the starting date of the fellowship is flexible, preferably within The postdoctoral candidate will work on a project that includes the study of an understudied target class of enzymes, with the goal of SAR profiling the target class to promote probe development.
Successful candidates will have a background in biochemistry, molecular biology, or cellular biology. Enzymology experience is preferred. Experience with drug screening and informatics are useful, but not required.
The trainee will learn to work in a team-based world-class drug discovery environment. The selected candidate must be able to work independently under team supervision. Please email a cover letter describing your research and career goals, a current curriculum vitae with a complete bibliography, and the names of and contact information for three references to ETB Team Lead Mark J. Henderson, Ph. The DMPK Core partners with collaborators academic institutions, foundations and private industry to conduct preclinical discovery and development studies leading to Investigational New Drug IND applications for new therapeutics.
The selected candidate will collaborate with team members to evaluate, develop and implement bioanalytical assays to quantify therapeutical biologics and its carriers in blood and tissues for assigned projects. Specific duties include providing bioanalytical strategies for novel therapeutical biologics, such as peptides, conjugated peptides, monoclonal antibodies, engineered human proteins, antibody-drug conjugates, oligonucleotides, mRNAs, gene therapies and other novel modalities.
The selected candidate also will be responsible for generating specific reagents for the assay development and will collaborate with biologists and researchers across different teams within NCATS to address project-specific needs.
Additional duties include quantitatively analyzing biological samples collected from preclinical pharmacokinetic and biodistribution studies, preparing documents for the regulatory filing purpose, and disseminating research via peer-reviewed publications and participating in scientific conferences and meetings. The selected candidate should possess strong oral and written communication skills and excellent interpersonal skills, including the ability to communicate clearly and succinctly in a timely manner.
The selected candidate will be expected to demonstrate a proven ability to collaborate with colleagues to achieve project, team and organizational goals. Applicants to this postdoctoral fellow position should hold a Ph.
Candidates with advanced knowledge and skills in high-performance liquid chromatography, mass spectrometers, electrochemiluminescence ligand binding device or related instruments will receive preferential consideration. Candidates also should have strong oral and written English communication skills and be able to work in a highly collaborative team setting.
The salary will be commensurate with experience based on the NIH Postdoctoral Intramural Research Training Award and Visiting Fellow scale ; medical insurance coverage will be provided. Please email a cover letter describing your interest in the position, including a career synopsis one to two pages , a current curriculum vitae with a complete bibliography, and the names of and contact information for at least three references to Xin Xu, Ph.
The review of applications will begin on July 1, , and will continue until the position is filled. Food and Drug Administration, and the U. The goals of the Toxicology in the 21st Century Tox21 program are to prioritize chemicals for further in-depth toxicological evaluation, identify mechanisms of chemical toxicity and develop predictive models for in vivo biological response in humans.
NCATS has a unique and exciting environment that employs state-of-art technologies for assay development, chemical screening and profiling for toxicology research. The selected candidate will engage in several activities, including analyzing large data sets generated from HTS assays; developing novel methods to identify and prioritize toxicity response pathways for assay development and compound testing; building predictive models for different in vivo toxicity endpoints using chemical structural data, genomic data and in vitro assay data; and generating testable hypotheses on compound mechanisms of toxicity.
The candidate should be familiar with public genomic and genetic databases and be capable of data mining using complex data sets. The successful candidate also should have experience building and integrating genomic databases and working at the interface of genomic and chemoinformatic information.
The fellow will work closely with informatics scientists and biologists in the DPI to aid in data interpretation and project development. Applicants to this position should possess a Ph.
A background in cheminformatics or bioinformatics, biology, chemistry or toxicology is preferred. Experience in 2-D or 3-D modeling, large data set manipulation or data mining is a plus. The ideal candidate should possess strong oral and written communication skills with a proven publication record in peer-reviewed journals. Applicants should be eligible to work in the United States for any employer. Annual stipends commensurate with experience are provided and are based on the NIH Postdoctoral Intramural Research Training Award and Visiting Fellow scale ; medical insurance coverage will be provided.
Please submit via email a cover letter that includes a research summary and describes your interest in the position, a current curriculum vitae with a complete bibliography, and the names of and contact information for at least three references to Ruili Huang, Ph.
The selected candidates will develop human functional neural 3-D tissue models as assay platforms for the discovery and development of new therapeutics for pain, addiction or overdose.
Applicants with a background in neurosciences, in vitro neural organotypic models and neural stem cells will receive preferential consideration. The selected candidates will develop and characterize functional 3-D neural organotypic assays for drug discovery and development.
Applicants to these postdoctoral fellow positions should possess a Ph. The ideal candidates will be expected to work independently as well-trained problem solvers in the production of 3-D neural organotypic models, including architectural and physiological validation, and develop functional assay readouts for drug screening.
They will keep accurate and complete records of all scientific experiments according to established procedures and ensure that these records and raw data are properly retained. They also will draft technical reports, manuscripts and patent applications and present work internally and externally to consultants and collaborators as needed.
Experience in techniques necessary to develop CNS and PNS assays for drug testing using tissues, including extracellular electrophysiological recording field potential or multi-unit , calcium imaging, neural stem cell and primary cell culture and associated analysis is required.
Experience with techniques such as histology, quantitative analysis of microscopy images, time-lapse microscopy is highly desired. Candidates with additional experience in physiology and pathology of pain, addiction or overdose, optogenetics microscopy, or tissue engineering or bioprinting techniques will receive preferential consideration.
Each candidate should be an independent thinker and team player able to work and multitask in a highly interactive, fast-paced environment. Please submit via email a cover letter that includes a research summary and describes your interest in the position, a current curriculum vitae with a complete bibliography, and the names of and contact information of at least three references to NCATSbioprinting mail.
The review of applications will begin immediately and will continue until these positions are filled. The selected candidate will work collaboratively with team members to evaluate, develop and implement in silico absorption, distribution, metabolism and excretion ADME models for assigned projects.
Specific duties include analyzing DMPK data using state-of-the-art methods and exploring new computational methodologies and approaches from the literature in a constant effort to improve existing models and reveal useful medicinal chemistry insights. The selected candidate also will be responsible for developing new structure-based computational models for predicting DMPK properties. They will collaborate with chemists and researchers across different teams within NCATS to address project-specific needs e.
Additional duties include disseminating research via peer-reviewed publications and participating in scientific conferences and meetings. They also should possess excellent interpersonal skills, including the ability to communicate clearly and succinctly in a timely manner.
The selected candidate will be expected to demonstrate a proven ability to work collaboratively with colleagues to achieve project, team and organizational goals. Applicants to this postdoctoral fellow position should possess a Ph. Candidates with advanced knowledge and skills in graph neural networks or equivariant neural networks will receive preferential consideration.
Experience working on cloud platforms — such as Amazon Web Services or Microsoft Azure or a similar high-performance computing environment — will be considered favorably. Applicants also should possess strong oral and written English communication skills and be able to work in a highly collaborative team setting. The salary will be commensurate with experience, based on the NIH Postdoctoral Intramural Research Training Award and Visiting Fellow scale ; medical insurance coverage will be provided.
Please email a cover letter describing your interest in the position, including a career synopsis one to two pages ; a current curriculum vitae with a complete bibliography; and the names of and contact information for at least three references to Pranav A.
Shah, Ph. Review of applications will begin on Jan. Multiple positions are available for motivated individuals to work in a translational science laboratory team environment with a focus on multiple target-based programs, including assay development, high-throughput screening and drug lead optimization.
Having safe and effective oral antiviral candidates ready for deployment in later-stage clinical trials against a newly emergent virus would save lives, reduce serious illness and prevent overwhelming surges in hospitalizations during a viral outbreak or pandemic.
NCATS will partner with extramural scientists and the private sector to advance drug discovery and development programs for oral antiviral candidates. NCATS can collaborate on projects with entry points anywhere along the development pipeline — and with flexible project exit points — to accelerate discovery and overcome the scientific, technical and enterprise barriers to delivering drug candidates ready for Phase 2 clinical trials in future pandemics. The selected candidates will work as part of a multidisciplinary team of innovative scientists using cutting-edge technologies for the development of antiviral drugs.
The postdoctoral fellows will be responsible for developing new algorithms for the prediction of protein—ligand interactions and deep generative models, developing and applying QSAR models and molecular modeling techniques for the virtual screening of compounds, and lead optimization efforts.
Candidates should be self-motivated, driven, thorough and careful experimentalists with the ability to multitask, think independently and work in a highly creative, interactive and fast-paced environment. In addition to teamwork, they also will be expected to work independently as well-trained problem solvers. The selected candidate will keep accurate and complete records of all scientific experiments according to established procedures and ensure that these records and raw data are properly retained.
They will draft technical reports, manuscripts and patent applications and present work to internal and external collaborators as needed. Candidates with previous experience with common cheminformatics libraries and data formats e. The candidates will work as part of a multidisciplinary team of innovative scientists using cutting-edge technologies for the development of antiviral drugs. The postdoctoral fellows will be responsible for prioritizing antiviral targets for therapeutic development, developing new algorithms for the detection of ligand binding sites, predicting their spectrum of activity against family members and assessing the potential for the development of resistance.
Fellows also will support lead discovery work for prioritized targets. The selected applicants will keep accurate and complete records of all scientific experiments according to established procedures and ensure that these records and raw data are properly retained. They will draft technical reports, manuscripts and patent applications and will present work to internal and external collaborators as needed. Candidates with previous experience with bioinformatics e.
The IFX is an interdisciplinary team of bioinformaticians, clinical informaticians, cheminformaticians and software engineers who collaborate closely with molecular biologists to augment the use of metabolomics and multi-omics analysis approaches to identify dysregulated pathways and putative therapeutic targets.
The selected candidate — a postdoctoral fellow in bioinformatics — will have a solid foundation in bioinformatics and biostatistics, including machine learning, and experience in cleaning, processing, and integrating metabolomic and other -omic datasets. He or she will develop novel bioinformatics methods to optimize the predictive capacity of metabolomics and -omic e. These novel approaches will augment the bioinformatics field by addressing issues not addressed by standard approaches. The selected candidate will interact closely with computational and noncomputational e.
In addition to working independently on collaborative translational research projects, the fellow also would be involved in building a computational infrastructure for the QC, analysis and interpretation of metabolomic and multi-omic profiles. The ideal candidate should possess a doctoral degree or equivalent in bioinformatics, biomedical informatics, or a related field and have demonstrated hands-on experience in leading the large-scale analysis of multi-omic data.
Experience with metabolomics data is strongly preferred. He or she should have demonstrated experience leveraging publicly available datasets, including their organization, cleaning and preprocessing. Basic knowledge and understanding of biology and chemistry is a plus. The selected candidate should have excellent interpersonal, verbal and written communication skills in English and should possess strong collaborative, organizational and recordkeeping skills; the ability to work productively as a member of a diverse and dynamic multidisciplinary team, managing multiple research studies simultaneously; and the desire to acquire new skills as required for research studies.
While the team is highly collaborative in nature, the pursuit of original computational research directions by the candidate is encouraged. Multiple positions are available for motivated individuals to work in a translational science laboratory team environment with a focus on multiple target-based programs including assay development, high-throughput screening and drug lead optimization. The candidates will work in the Functional Genomics Laboratory using cutting-edge technologies to develop assays and study viral infections for drug discovery for SARS-CoV-2 and other viruses of pandemic potential.
Please email a cover letter describing your research and career goals, a current curriculum vitae with a complete bibliography, and the names of and contact information for three references to NCATS APP Hiring at ncatsfglrecruitment mail. The branch partners with external collaborators who specialize in specific disorders, creating a multidisciplinary team of innovative scientists with expertise in assay development, high-throughput and high-content screening, automation engineering, bioinformatics, and various -omics technologies.
He or she will use cutting-edge cell biology and bioassay technologies for the development of disease-relevant screening assays and will be involved in all aspects of the implementation of small-molecule screening programs, including assay design, assay development and optimization, high-throughput screening, data analysis, and mechanism-of-action studies, with the goal of developing assay technologies and novel pharmacological probes.
The selected candidate should be able to work independently under team supervision. He or she will keep accurate and complete records of all scientific experiments according to established procedures and ensure that these records and raw data are retained properly. The candidate also will draft technical reports and manuscripts and will present their work internally and to external collaborators as needed.
Experience with cancer and epigenetics — including assays to assess chromatin organization and modifications — is highly desirable. The selected candidate should be an independent thinker, a team player, and able to work in an interactive, fast-paced environment.
Annual stipends are provided commensurate with experience based on the NIH Postdoctoral Intramural Research Training Award and Visiting Fellow scale ; medical insurance coverage will be provided. The candidates will work as part of a multidisciplinary team of innovative scientists using cutting-edge technologies to develop assays and study viral infections for drug discovery for SARS-CoV-2 and other viruses of pandemic potential.
Candidates with previous experience with a variety of techniques — including molecular and cell biology, assay development, high-throughput screening, virology, biochemical assays and cell culture — are preferred.
The selected candidate should have expertise in tissue biofabrication to help establish a portfolio of complex physiologically relevant 3-D tissue models as predictive screening platforms to study viral infections and conduct drug testing. Applicants should have additional expertise in histology, fluorescence microscopy and experience working with primary cells or induced pluripotent stem cell-derived cells. The selected candidate will work as part of a multidisciplinary team of innovative scientists, using cutting-edge biofabrication methodologies — including 3-D bioprinting, quantitative cell imaging, histology, assay development, drug screening, data science and other -omics technologies including scRNAseq — to develop advanced cellular models for drug discovery and development.
The selected candidate should be a self-motivated, driven, thorough and careful experimentalist with the ability to multitask, think independently and work in a highly creative, interactive and fast-paced team environment.
They also will be expected to work independently as well-trained problem solvers in tissue biofabrication, including architectural and physiological validation of the tissues.
The selected candidates also should be eligible to work in the U. Each applicant to this postdoctoral position should possess a Ph. Candidates with previous experience developing and characterizing complex 3-D cell-based functional assays — including work in areas such as organoids, tissue chip or biofabricated tissues, biomaterials, cell imaging, histology and engineering of cells with biosensors — will be considered favorably.
Please submit, in PDF format, a cover letter that includes a research summary and describes your interest in the position, a current curriculum vitae with a complete bibliography, and the names of and contact information for two to three references, including your current supervisor, to NCATSbioprinting mail. The selected postdoctoral fellow will work under the mentorship of a biology team leader in an interactive laboratory environment and be exposed to cutting-edge high-throughput screening, assay biology, bioinformatics, medicinal chemistry and disease-relevant biological models.
They will implement antibody discovery technologies including phage display , directed evolution, and related technologies to produce and characterize antibodies relevant to diseases and conditions related to pain, addiction and overdose, and other public health emergencies, such as the SARS-CoV-2 pandemic.
The selected applicant will apply cutting-edge cell biology and bioassay technologies for the development of disease-relevant antibody selection and screening assays and will be involved in all aspects of the implementation, including assay design, assay development and optimization, antibody screening, protein engineering, data analysis and mechanism-of-action studies.
They will draft technical reports and manuscripts and will present work internally and to external collaborators as needed. Experience with antibody phage display technologies — including panning, ELISA, and protein purification — and an understanding of antibody domain architecture are highly desirable.
The candidate should be an independent thinker, a team player, and able to work in a very interactive, fast-paced environment. The selected candidate will work on a multidisciplinary team to identify clinical candidates to address unmet medical needs. The postdoctoral fellow will be responsible for designing and synthesizing compounds for structure-activity relationship and structure-property relationship studies, developing new technologies to accelerate drug discovery, presenting results in internal and external meetings, and writing reports and manuscripts.
The ideal candidate should be self-motivated, possess a strong work ethic, have keen attention to detail, and be able to work on multiple projects simultaneously. The candidate should possess strong oral and written communication skills with a proven publication record in peer-reviewed journals. Please submit a cover letter describing your interest in the position, including a research summary, a current curriculum vitae, and the names of and contact information for three references to Wenwei Huang, Ph.
Gerhold, Ph. This laboratory also develops novel human cellular 3-D and co-culture models to study cardiovascular disease, as well as neurological and renal diseases. In addition to conducting cutting-edge laboratory research, DPI scientists work in a team-based environment and collaborate with more than research organizations worldwide. The selected candidate — a self-motivated, collaborative postdoctoral fellow — will complete the development and implementation of a novel high-throughput screening method that quantifies the expression of selected genes in cultured mammalian cells.
The unprecedented throughput of this method will enable the screening of large chemical libraries of environmental toxicants or drug candidates. The successful applicant will work with collaborators who have developed induced Pluripotent Stem Cell iPSC —derived endothelial cells , as well as 3-D endothelial cell models that incorporate shear flow and co-culture with vascular smooth muscle cells. The postdoctoral candidate also will have opportunities to collaborate with scientists both within and outside of NCATS on additional projects.
The selected candidate is expected to present results of ongoing work at meetings such as internal group meetings and national conferences and submit their work for publication in scientific journals. The ideal candidate will possess a doctoral degree i. Applicants should possess molecular biology expertise and mammalian cell culture skills.
Applicants also should possess strong oral and written English communication skills. Applicants with additional expertise in vascular biology or high-throughput screening will receive preferential consideration. Applicants should be U. Please submit a cover letter describing your interest in the position, a current curriculum vitae with a complete bibliography, and the names of and contact information for three references to David L.
The selected candidate should have expertise in mass spectrometry, high-performance liquid chromatography HPLC and proteomics fields.
Applicants with additional expertise in protein biochemistry, automation systems and high-throughput screening will receive preferential consideration. The Analytical Chemistry Core Facility maintains a state-of-the-art laboratory, the mission of which is to support chemistry research throughout the Center. The laboratory has a variety of instrumentation utilizing various analytical techniques, including liquid chromatography-mass spectrometry, gas chromatography-mass spectrometry, high-resolution mass spectrometry and nuclear magnetic resonance to facilitate early-stage chemical development.
The laboratory manages several cutting-edge mass spectrometers with the capability to perform high-throughput sample analysis, peptide and protein analysis top-down and bottom-up , post-translational modification analysis, multiple reaction monitoring MRM , proteomics, metabolomics, and ultra-high-resolution analysis of small molecules.
The postdoctoral fellow will work as part of a multidisciplinary team of innovative scientists using the available resources to develop novel methods and assays for high-throughput proteomics analysis and mass spectrometry-based compound screening. The postdoctoral fellow will be expected to work independently as a well-trained problem solver in the areas of mass spectrometry and HPLC.
He or she will manage, troubleshoot and regularly maintain the instrumentation. The fellow will be expected to prepare samples of various modalities prior to analysis. The fellow also will be required to keep accurate and complete records of all scientific experiments according to established procedures and ensure that these records and raw data are properly retained.
He or she will draft technical reports, manuscripts and patent applications, as well as present work at internal and external meetings.
The successful applicant should possess a Ph. Familiarity with the RapidFire high-throughput sampling system and protein biochemistry is necessary. Training in the areas of metabolomics, lipids analysis, MRM, intact protein and protein top-down analysis is desirable.
The ideal candidate should be self-motivated, possess a strong work ethic, have a keen attention to detail, and be able to work on multiple projects simultaneously. Excellent analytical, organizational and time-management skills are required.
Please submit a cover letter describing your interest in the position, including a research summary one to two pages ; a current curriculum vitae with a complete bibliography; and the names of and contact information for at least three references to Christopher A.
LeClair, Ph. The selected candidates should have expertise in biofabrication, biomaterials or microfluidics to help establish a portfolio of functional, physiologically complex 3-D tissue models as predictive screening platforms for toxicity and efficacy drug testing. Applicants with additional expertise in microphysiological systems, immunology, neuroscience and production of induced pluripotent stem cell-derived cells will receive preferential consideration.
The candidates will work as part of a multidisciplinary team of innovative scientists, using cutting-edge biofabrication methodologies—including 3-D bioprinting, quantitative cell imaging, histology, assay development, drug screening, data science and other cutting-edge -omics technologies — to develop advanced cellular models for drug discovery and development.
They also will be expected to work independently as well-trained problem solvers in biofabrication and microfluidics, including on architectural and physiological validation of the tissues. The successful candidates will keep accurate and complete records of all scientific experiments according to established procedures and ensure that these records and raw data are properly retained.
Each applicant for this postdoctoral position should possess a Ph. Candidates with previous experience developing and characterizing complex 3-D cell-based functional assays—including work in such areas as organoids or biofabricated tissues, biomaterials, microfluidic systems, cell imaging, histology and engineering of cells with biosensors—as well as experience using bioprinting techniques, will be considered favorably.
Candidates with a strong background in immunology and tissue engineering with induced pluripotent stem cell-derived cells are encouraged to apply. TDB develops new systems, novel approaches and methodologies to achieve conceptual breakthroughs in preclinical therapeutics. The branch also provides collaborative access to technology and expertise in the scientific disciplines of early-discovery biology and medicinal chemistry; drug metabolism and pharmacokinetics; toxicology; and chemistry, manufacturing and controls synthesis and formulation.
The selected candidate — a self-motivated, collaborative postdoctoral fellow — will join an interdisciplinary team with a focus on profiling different cell types and responses in the context of rare genetic diseases, infectious diseases and drug treatments.
The fellow will collaborate with researchers in other universities and Institutes and will learn preclinical drug development from colleagues in multidisciplinary project teams.
The fellow should obtain extensive experience and skills in this training program that can be applied toward translational research for therapeutics development. The ideal candidate should possess a doctoral degree or equivalent in biology, computer sciences, bioinformatics or a related discipline, with one to three years of relevant research experience. Candidates should possess strong computer programming skills in R and other required languages e.
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Core Responsibilities The postdoctoral fellow will be responsible for designing and synthesizing compounds for structure-activity relationship and structure-property relationship studies, developing new technologies to accelerate drug discovery, presenting results in internal and external meetings, and writing reports and manuscripts. Core Responsibilities The selected candidate — usajobs gov federal jobs hiring posters designer self-motivated, collaborative postdoctoral fellow — will complete the development and implementation of a novel нажмите для продолжения screening method that quantifies the expression of selected genes in cultured mammalian cells. The selected candidate also will be responsible for developing new structure-based computational models for predicting DMPK usajobs gov federal jobs hiring posters designer. Please submit a cover letter describing your interest jiring the position, a posterrs curriculum vitae with a complete bibliography, and the names of and contact information for three dederal to NCATSstemcellhiring mail. The SCTL focuses on translating human pluripotent stem перейти, such as induced pluripotent stem cells, into clinical applications and drug discovery by developing innovative technologies, methods and comprehensive multi-omics data sets through differentiation into relevant cell types in 2-D and 3-D cell culture systems.
